http://www.clontech.com/AIT/Ecommerce/Clontech/ProductCatalog.aspx?item=139040

http://www.clontech.com/clontech/techinfo/manuals/PDF/PT3383-1.pdf

The In Vivo Kinase Assay Kits facilitate the study of a drug candidate, gene, or
molecule of interest and their in vivo effects on specific signaling pathways. In
particular, these kits allow you to determine whether a specific transcriptional
activator (transactivator) in a signaling pathway has been directly or indirectly
phosphorylated. Currently, In Vivo Kinase Assay Kits are available for studying
the following pathwaysœôòôMAPK, p38K, JNK & PKA. For a simplified schematic
overview of the MAPK, p38K, JNK or PKA signaling pathways, see Appendix A.
Each kit includes four vectors: a transactivator expression vector (pTet-ELK,
-ATF, -JUN, or -CREB), a reporter vector (pTRE-Luc), a positive control vector
(pTet-Off), and a negative control vector (pTet-Neg). See Appendix C for in vivo
kinase vector maps and descriptions.


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